| Game | Updated |
| Sacred 2: Fallen Angel | 01/27/2011 |
| Saints Row | 05/16/2011 |
| Saints Row 2 | 04/5/2011 |
| Sam & Max Save the World | 07/11/2011 |
| Samurai Shodown Sen | 02/27/2011 |
| Samurai Warriors 2 | 05/30/2011 |
| Samurai Warriors 2 Empires | 10/29/2011 |
| Saw II: Flesh & Blood | 08/3/2011 |
| Saw: The Videogame | 06/6/2011 |
| Scott Pilgrim vs. The World: The Game | 03/18/2011 |
| Scrap Metal | 06/24/2011 |
| Section 8 | 07/27/2011 |
| SEGA Rally Revo | 08/9/2011 |
| SEGA Soccer Slam | 07/10/2011 |
| SEGA Superstars Tennis | 02/21/2011 |
| Shadow Complex | 09/8/2011 |
| Shank | 08/6/2011 |
| Shrek the Third | 04/15/2011 |
| Sid Meier’s Pirates! Live the Life | 12/11/2011 |
| Silent Hill: Homecoming | 01/5/2012 |
| Singularity | 08/22/2011 |
| Skate | 02/25/2011 |
| Skate 2 | 07/18/2011 |
| Skate 3 | 11/28/2011 |
| Small Arms | 10/20/2011 |
| Snake360 | 03/4/2011 |
| Sneak King | 06/15/2011 |
| Sniper: Ghost Warrior | 09/19/2011 |
| Snoopy: Flying Ace | 09/14/2011 |
| Sonic & Knuckles | 05/22/2011 |
| Sonic & SEGA All-Stars Racing with Banjo Kazooie | 03/1/2011 |
| Sonic Adventure | 12/31/2011 |
| Sonic Free Riders | 01/30/2011 |
| Sonic the Hedgehog | 07/27/2011 |
| Sonic the Hedgehog 4: Episode I | 01/17/2011 |
| Sonic Unleashed | 01/26/2011 |
| Sonic’s Ultimate Genesis Collection | 12/12/2011 |
| Soulcalibur | 02/6/2011 |
| Soulcalibur IV | 11/25/2011 |
| Soulcaster | 05/30/2011 |
| South Park Let’s Go Tower Defense Play! | 01/25/2011 |
| Space Invaders Extreme | 12/6/2011 |
| Space Invaders Infinity Gene | 04/9/2011 |
| Spider-Man 3 | 07/11/2011 |
| Spider-Man: Friend or Foe | 11/2/2011 |
| Spider-Man: Shattered Dimensions | 10/5/2011 |
| Spider-Man: Web of Shadows | 12/5/2011 |
| Splatterhouse | 09/17/2011 |
| Split/Second | 12/27/2011 |
| Splosion Man | 12/24/2011 |
| SpongeBob’s Truth or Square | 10/19/2011 |
| Star Ocean: The Last Hope | 08/31/2011 |
| Star Trek: D-A-C | 03/19/2011 |
| Star Wars: The Clone Wars — Republic Heroes | 03/8/2011 |
| Star Wars: The Force Unleashed | 08/01/2012 |
| Star Wars: The Force Unleashed — Ultimate Sith Edition | 10/6/2011 |
| Star Wars: The Force Unleashed II | 02/14/2011 |
| Street Fighter IV | 03/30/2011 |
| Stuntman: Ignition | 04/15/2011 |
| Super Meat Boy | 04/22/2011 |
| Super Robot Taisen XO | 08/15/2011 |
| Super Street Fighter II Turbo HD Remix | 01/25/2011 |
| Super Street Fighter IV | 10/10/2011 |
| Superman Returns: The Videogame | 07/4/2011 |
| Surf’s Up | 12/30/2011 |